by and large(by and)

by 是通过某种方法 by something1。表示以一般的方法或方式。如： No one in those days could live by writing poems. 2。表示传达、传递的方式或煤介。如： How did you send the letter, by airmail or by ordinary mail?through 是通过某种途径 through some methods1.He bought the antique vase through a dealer.他通过一个商人买到这只古花瓶2.He became rich through hard work.他靠努力工作而致富。in 是以某种方式，用或通过某种媒介 Made with or through the medium of:1.paid in cash.以现金支付2.a statue in bronze; a note written in German.青铜雕像；用德语写的便笺with 是通过…的方式或媒介。以通过…的存在或使用1．eat with a fork; made us laugh with his jokes.用叉子吃饭；以他的笑话引我们发笑2．a pillow stuffed with feathers; balloons filled with helium.用羽毛装满的枕头；装满氦气的气球